DOSAGE AND ADMINISTRATION. The usual dose of DYAZIDE (hydrochlorothiazide and triamterene) is one or two capsules given once daily, with appropriate monitoring of serum potassium and of the clinical effect (see WARNINGS, Hyperkalemia). Hydrochlorothiazide is the generic form of the brand-name drug Microzide. It's a prescription diuretic ( water pill ) that's used to treat high blood pressure and other conditions. Usual Adult Dose for Hypertension. Initial dose: 1 tablet (12.5 mg-160 mg) orally once a day Maintenance dose: Titrate as necessary (every 1 to 2 weeks) up to a maximum of 25 mg-320 mg orally once a day Usual Adult Dose for Edema. Usual dose: 25 mg to 100 mg orally once or twice daily Comments:-Some patients respond to intermittent therapy, (i.e., administration on alternate days or on 3 to 5 days each week). Hydrochlorothiazide oral tablet is only available as a generic drug. Hydrochlorothiazide comes as a tablet or capsule that you take by mouth. Hydrochlorothiazide oral tablet is used to treat high. DOSAGE AND ADMINISTRATION. The usual dose of MAXZIDE-25 MG is one or two tablets daily, given as a single dose, with appropriate monitoring of serum potassium (see WARNINGS). Hydrochlorothiazide (Microzide and others) is a drug used to treat excessive fluid accumulation and swelling (edema) of the body caused by heart failure, cirrhosis, chronic kidney failure, corticosteroid medications, and nephrotic syndrome. Side effects, dosage, drug interactions, and pregnancy and breastfeeding safety are provided. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Initially, 1 tablet bisoprolol; hydrochlorothiazide 2.5 mg/6.25 mg PO once daily. Titrate dosage every 2 weeks up to the maximum dosage based on clinical response. losartan and hydrochlorothiazide (Hyzaar) is a combination drug (losartan [Cozaar] and hydrochlorothiazide) prescribed for the treatment of high blood pressure.