Headaches, muscle pain, and joint pain are common side effects that have been reported with Lipitor. Side effects that are less common include lack of appetite, back pain, and constipation. Niacin can increase the harmful side effects of Lipitor on muscle, which can in turn harm the patient's kidneys and lead to renal failure, according to the Mayo Clinic. Learn about Lipitor (Atorvastatin Calcium) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. While the accumulated safety record for Lipitor is excellent, as with all drugs there are associated side effects in susceptible patients that may become apparent only after long-term usage. What other drugs will affect Lipitor? Certain other drugs can increase your risk of serious muscle problems, and it is very important that your doctor knows if you are using any of them. Lipitor (atorvastatin) is a statin used for the treatment of elevated total cholesterol, LDL, triglycerides, and to elevate HDL cholesterol. Side effects of Lipitor include: Always discuss possible side effects with a healthcare provider lipitor who knows your generic for lipitor side medical history. Multum does not assume any responsibility for side any aspect of healthcare administered with the lipitor side aid of information Multum provides. Lipitor can cause serious side effects. Stop taking the drug and call your doctor right away if you have any of these serious side effects: Unexplained muscle pain, tenderness, or weakness Lipitor (atorvastatin) is a prescription drug used to lower blood cholesterol. Common side effects are fatigue, flatulence (gas), heartburn, and constipation. Drug interactions, dosage, and pregnancy and breastfeeding safety information are provided. Learn about the potential side effects of Lipitor (atorvastatin). Includes common and rare side effects information for consumers and healthcare professionals.