Each TYLENOL Severe Allergy Caplet contains acetaminophen 500 mg and diphenhydramine HCl 12.5 mg. Each Maximum Strength TYLENOL Allergy Sinus Night Time Caplet contains acetaminophen 500 mg, diphenhydramine HCl 25 mg, and pseudoephedrine HCl 30 mg. Chlorpheniramine comes as a tablet, a capsule, an extended-release (long-acting) tablet and capsule, a chewable tablet, and a liquid to take by mouth. How to Clear a Sinus Infection. Your sinuses are cavities in your face that serve various functions, including moistening the air you breathe and producing mucus to trap and expel pathogens from your body. Sometimes, the sinuses can't. Find patient medical information for Tylenol Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Alleviate the pain and pressure of sinus headaches and relieve chest congestion with TYLENOL® Sinus Severe Daytime Caplets. Try this non-drowsy daytime formula. Acetaminophen is used to relieve mild to moderate pain from headaches, muscle aches, menstrual periods, colds and sore throats, toothaches, backaches, and reactions to vaccinations (shots), and to reduce fever. TYLENOL® Sinus Congestion & Pain tackles tough sinus pain that can result in a headache, effective relief so you can get back to your day. Review the Infants’ and Children’s TYLENOL® dosage chart to better understand how to administer acetaminophen to your child based on their weight or age. Easy-to-read patient leaflet for Tylenol Cold. Includes indications, proper use, special instructions, precautions, and possible side effects. You can indeed take both of these medications at the same time, and in fact your doctor may recommend that you do so.