Further, long-term heavy alcohol use while taking an antidepressant such as Cymbalta can make your antidepressant less effective. As a result, your treatment may take longer or be compromised. (I stopped going to that doctor and stopped taking the Cymbalta. Big, big mistake -- had awful, terrible agony from stopping Cymbalta cold turkey -- felt like electric jolts in my brain.) Only this time the diarrhea didn't stop when the medication stopped. It's abated some since then -- August 2007 -- but has never fully gone away. Continued. If the medicine upsets your stomach, you can try taking it with a meal or some crackers. You should not drink alcohol when taking Cymbalta. I’m currently taking cymbalta and I’m experiencing severe diarrhea. My dose doubled to 60mg about a week ago and I’ve had severe diarrhea for about a week. Since you did, too I’m going to call my dr tomorrow. Hope you’re doing well! Find information about common, infrequent and rare side effects of Cymbalta Oral. I would think the side effects would go away within a month or so. If not they may just be a side effects that will be there forever while taking this medication. Diarrhea is found among people who take Cymbalta, especially for people who are female, 60+ old , have been taking the drug for 1 month, also take medication Lyrica, and have Pain. This study is created by eHealthMe based on reports of 107,187 people who have side effects when taking Cymbalta from FDA, and is updated regularly. Breastfeeding while taking Cymbalta is not recommended. Our Cymbalta Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Cymbalta gave me diarrhea too. It also did not help with my mood and for those two reasons, i discontinued the medication. There are many other medications, in many other classes to try. Just wondering if the Diarrhea will eventually stop. I've been on cymbalta for a week now. That is really my only concern. It has really helped with my anxiety already.