After feeeling like ive reached the end if my sanity and tether i went to visit my gp who was very helpful and reassuring. She prescribed 50mg of serataline in addition to my 80mg slow realease propanalol. By continuing to use this site you consent to the use of cookies on your device as described in our cookie policy unless you have disabled them. I just started taking Zoloft abut 3 days ago. I have really bad anxiety and since I started taking it I am even more anxious and I get really shaky and I cannot control it. I am taking zoloft for anxiety, not depression. I was started on 25mg, I'm now on 100 mg. After I take the medication, I get real nervous feeling. First few days of Zoloft, feeling very anxious.? I'm on my fifth day of taking Zoloft for my anxiety problem. I had 25mg for the first two days and then 50mg/day after that (per my doctor's instructions). Hope this helps someone who is reading all the comments about people feeling better after a just a few weeks and thinking its taking too long so zoloft won't work. it does, just some of us take a little longer to feel the effects. Hang in there good times are coming. I started taking 50mg of zoloft 8 days ago. The first 2 days were fine, just a little spacy feeling but then on day 3, I started feeling anxiety and kind of a speedy feeling. I was taking 25mg of zoloft, and just went up to 50mg of zoloft. I am feeling very anxious and nervous. Is this normal, and should it stop as my body adjust? Has anyone else had this? sweetpotatoe57 I am feeling very anxious and nervous. This risk is higher if a person is also taking other serotonin-related medications like triptans (a common migraine medication), tricyclic antidepressants, or the pain medication, Ultram (tramadol), but can occur with taking Zoloft alone, as well. I have been diagnosed with depression. My doctor has prescribed 50 mg of Zoloft a day, taken in the evening. I have been taking this for 2 weeks now.