Depo-Provera will not be effective in preventing pregnancy if you do not receive an injection every 3 months. If you plan to continue using this medicine, get the missed injection as soon as possible. Medroxyprogesterone acetate (MPA), also known as depot medroxyprogesterone acetate (DMPA) and sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type. How does the birth control shot work? The birth control shot (sometimes called Depo-Provera, the Depo shot, or DMPA) contains the hormone progestin. Progestin stops you from getting pregnant by preventing ovulation. Depo-Provera is a contraceptive method for women. It’s made of a hormone similar to progesterone. It's a shot that a doctor gives you in the arm or buttocks. Each shot works for up to 12 to 14. Depo-Provera is the brand name of the birth control shot. It’s an injectable form of the drug depot medroxyprogesterone acetate, or DMPA for short. DMPA is a man-made version of progestin, a. How do you use Depo-Provera? Depo-Provera is a prescription and the injection is obtained from your healthcare provider every 11 to 13 weeks. The healthcare provider will inject the synthetic hormone in the upper arm or in the buttocks. Does Depo-Provera affect sex drive? I am really anti-chemicals.but somewhat prepared to take permanent measures against becoming pregnant again. In the meantime, we will use Depo (I was on it for 3 years when I was only somewhat sexually active, and probably at my peak!). Not everyone gains weight on Depo Provera, and it's probably possible to reduce the chance you do by engaging in regular exercise and eating a quality diet. I just started taking Depo on April 21, 2014 (three days after I had a miscarrige). Got mine from Planned Parenthood since I didn't have a primary care doctor at the time. Depo Provera can be used by most women who do not have any serious medical problems and by many women who use other forms of contraception. It may also be suitable for women who cannot take the combined pill for medical reasons.