Sinus Infection Treatment and Remedy. If you are suffering from sinusitis then it is essential for you know the sinus infection treatment remedies available. An overview of a constant runny nose that produces a clear liquid and mucus in adults and toddlers, and that sometimes accompanied with cough and sneezing. Benadryl Allergy & Sinus Headache. Generic Name: acetaminophen, diphenhydramine, and phenylephrine (a SEET a MIN oh fen, DYE fen HYE dra meen, and FEN il EFF rin) Your Pregnancy Matters Which over-the-counter cold medications are safe during pregnancy? January 9, 2018 Explains the medication diphenhydramine (Benadryl), a drug used for the relief of nasal and non-nasal symptoms of various allergic conditions such as seasonal hay fever, allergic conjunctivitis, insomnia, and motion sickness. Are natural or alternative remedies safe to use during pregnancy? Just because a product is labeled natural doesn't necessarily mean it's safe to take during pregnancy. Safe to take: Regular and extra-strength Tylenol (acetaminophen) A cold compress and rest can help alleviate muscle pain and headaches during pregnancy, but if you need additional relief, your. Benadryl products aren’t approved for use in babies (see warning above). Over-the-counter oral Benadryl products are only approved for use in children ages 6 years and older. Benadryl (Diphenhydramine) is often better than other antihistamines at treating allergy symptoms and hives. It can provide quick relief of allergy symptoms for both kids and adults. I have taken half doses of Mucinex D daily (one pill instead of two every 12 hours) for the past 3 years and I suffer no side effects except relief from thick mucus and recurring sinus infections.