Rapid treatment of status epilepticus (SE) is associated with better outcomes. Diazepam and midazolam are commonly used, but the optimal agent and administration route is unclear. Search of PubMed, Web of Knowledge, Embase, Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Alcohol consumption with this medication can increase sedation, confusion and may result in loss of conciousness (central nervous system depression). III – Gestion des status epilepticus. Conclusion. 6 INTRODUCTION. L’épilepsie est une maladie relativement répandue chez le chien (5 % des 2224 cas de neurologies référés vus par Jaggy et Bernardini entre 1989 et 1994 (1998)) et connue depuis longtemps : dès le 19ième siècle, le physicien John Hughlings Jackson arrive à la conclusion que les crises d’épilepsie sont dues à des. Status epilepticus (SE) is a single epileptic seizure lasting more than five minutes or two or more seizures within a five-minute period without the person returning to normal between them. Previous definitions used a 30-minute time limit. The seizures can be of the tonic–clonic type, with a regular pattern of contraction and extension of the. Diazepam or clonazepam, given intravenously, is generally the drug of choice for the emergency treatment of convulsive status epilepticus. Intravenous diazepam may be difficult to administer to the young convulsing child and, because of the need for intravenous access, is not ideal for rapid treatment in the community by non-medical carers. Usual Adult Dose for Status Epilepticus. PARENTERAL:-Initial dose: 5 to 10 mg IV once, repeated at 10 to 15 minute intervals to a maximum dose of 30 mg if necessary Comments:-The IV route is preferred; however, the IM route may be used if IV administration is impossible.-Treatment may be repeated every 2 to 4 hours, but active metabolites may persist during readministration.-Patients with. SUMMARY. Valium has proved to be one of the most effective drugs we have used in the treatment of status epilepticus. We have given one or more injections intravenously or intramuscularly, and also used up to 100 mg daily in a slow intravenous drip. Alcohol consumption with this medication can increase sedation, confusion and may result in loss of conciousness (central nervous system depression). Medscape - Antianxiety, antiseizure-specific dosing for Valium, Diastat (diazepam), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Status epilepticus is an under-recognized health problem associated with substantial morbidity and mortality. An estimated 152,000 cases occur per year in the United States, resulting in 42,000.