Learn about Augmentin (Amoxicillin Clavulanate) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Find patient medical information for Amoxicillin-Potassium Clavulanate Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Pharmacokinetics. Amoxicillin and clavulanate potassium are well absorbed orally. Clavunate is rapidly absorbed with a bioavailability of 60 % and it can be given parenterally. Amoxicillin and Clavulanate Potassium reference guide for safe and effective use from the American Society of Health-System Pharmacists (AHFS DI). AUGMENTIN XR® (amoxicillin and clavulanate potassium) DESCRIPTION. AUGMENTIN XR (amoxicillin and clavulanate potassium) extended release tablet for oral use is an antibacterial combination consisting of the semisynthetic antibacterial amoxicillin (present as amoxicillin trihydrate and amoxicillin sodium) and the β-lactamase inhibitor. Before taking amoxicillin and clavulanic acid, tell your doctor and pharmacist if you are allergic to amoxicillin (Amoxil, Trimox, Wymox), clavulanic acid, penicillin, cephalosporins, any other medications, or any of the ingredients in amoxicillin and clavulanic acid preparations. Amoxicillin is a penicillin antibiotic that fights bacteria in the body. Clavulanate potassium is a beta-lactamase inhibitor that helps prevent certain bacteria from becoming resistant to amoxicillin. Amoxicillin and clavulanate potassium is approved for treating the above infections only when they are caused by certain types of bacteria. Not all bacteria (and no viruses) will respond to the medication. Amoxicillin and clavulanate oral suspension is an antibiotic used to treat ear infections that have come back or have not gone away in children. You should not use this medicine if you have severe kidney disease, if you have had liver problems or jaundice while taking amoxicillin and clavulanate potassium, or if you are allergic to any penicillin or cephalosporin antibiotic, such as Amoxil, Ceftin, Cefzil, Moxatag, Omnicef, and others.