Comment in Drug Ther Bull. 2013 Nov;51(11):125. Tadalafil is a phosphodiesterase type-5 (PDE5) inhibitor licensed for the treatment of erectile dysfunction (ED) in adult males (Cialis-Lilly) and for the management of pulmonary arterial hypertension (Adcirca-Lilly).(1) The 5mg tablet was licensed in Epidemiological data link erectile dysfunction (ED) and benign prostatic hyperplasia (BPH)-associated lower urinary tract symptoms (LUTS), two highly prevalent conditions in aging men, assuming common pathophysiological pathways. Nowadays, many men may develop the condition called prostate gland enlargement of benign prostatic hyperplasia when getting older, and it causes a set of annoying urinary symptoms. Tadalafil, sold under the brand name Cialis among others, is a medication used to treat erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension. What are the side effects of using tadalafil (Cialis) for benign prostatic hyperplasia (BPH)? ANSWER Tadalafil (Cialis) is the only drug approved by the FDA for BPH, also called enlarged prostate. Detailed Tadalafil dosage information for adults. Includes dosages for Benign Prostatic Hyperplasia, Erectile Dysfunction and Pulmonary Hypertension; plus renal, liver and dialysis adjustments. User Reviews for Tadalafil to treat Benign Prostatic Hyperplasia. Also known as: Adcirca, Cialis. The following information is NOT intended to endorse drugs or recommend therapy. Tadalafil (Cialis) not only helps with benign prostatic hyperplasia symptoms (BPH) but also associated erectile dysfunction. People diagnosed with benign prostatic hyperplasia (non-cancerous overgrowth of the prostate; BPH) can experience erectile dysfunction (ED). This is the inability to get or keep an erection firm enough to have sexual intercourse.