You can use this table as an instrument to see how much Benadryl (Diphenhydramine) you can give your dog. You should administer this dosage every 8 hours/3 times a day. You should administer this dosage every 8 hours/3 times a day. my dog scratches too much she has ot got flees. we use preventive on her. we use oatmeal soap for her bath. we give her childrens benadryl-d (childrens). our vet has no idea why she scratches so much … How Much Benadryl Do I Give A 10lb Dog. Braintraining4dogs.com: Brain Training for Dogs | By Braintraining4dogs.com is tracked by us since January, 2018. The routine dose of Benadryl is 1-2mg per pound of dog. So if your dog weighs 10 pounds, she could have 1/2 - 1 of the 25mg tablets. So if your dog weighs 10 pounds, she could have 1/2 - 1 of the 25mg tablets. B+ How Much Benadryl Should I Give My 10lb Dog Get Your Dog to Listen to You Now! Proven Training Method, Hands Off Dog Training. Benadryl for Dogs: The Do’s & Don’ts, Dosage, Side Effects, And More If your dog or emotional support animal suffers from severe allergies or allergic reactions to things around them, then you know how hard it is to watch them go through that pain. Available over-the-counter, most Benadryl tablets are 25 mg each--but it is important to always check the label ( a children's Benadryl might be best for small dogs). Abiding by the one mg/pound dose, one 25 mg tablet would be the correct dose for a 25-pound dog. The dose can be repeated twice in the day. The guidelines for dosage in regard to dogs is 1/2mg. to 2mg. per pound. For instance if a dog (puppies) included weighs 15 pounds, the dog could have. Giving Benadryl to your dog: should you do it? Is it helpful and harmless? Or is Benadryl for dogs dangerous and a bad idea? Used properly, in the right situations, Benadryl can be a lifesaver—preventing headaches and alleviating discomfort for your dog. If Benadryl hasn't been recommended by your vet, it may be worth calling the veterinarian surgery and asking very simply if the medicine is safe for your pet to take.