Sensory disturbances most frequently reported adverse event. The table above lists the ten most commonly reported adverse events to sumatriptan. Sumatriptan is indicated for the acute treatment of migraine, with or without aura, and the acute treatment of cluster headache. Learn about side effects, drug interactions, dosages, warnings, and more. Sumatriptan is a headache medicine that narrows blood vessels around the brain. Sumatriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms. John P. Cunha, DO, FACOEP. John P. Cunha, DO, is a U.S. board-certified Emergency Medicine Physician. Dr. Cunha's educational background includes a BS in Biology from Rutgers, the State University of New Jersey, and a DO from the Kansas City University of Medicine and Biosciences in Kansas City, MO. This is a combination product containing sumatriptan, a selective 5-HT1 receptor agonist, and naproxen sodium, an arylacetic acid NSAID, in a fixed combination of sumatriptan 85 mg and naproxen sodium 500 mg. Migraine relief. Treatments for the relief of migraine headaches on prescription: Sumatriptan tablets and Imigran sprays. Buy low cost Imigran sprays and sumatriptan tablets from Dr Fox online doctor, posted from UK pharmacy (from £9.80). Migraine is a primary headache disorder characterized by recurrent attacks. Approximately 44.5 million U.S. adults (18% to 26% of women and 6% to 9% of men) have experienced a migraine, according. Sumatriptan Succinate is the succinate salt form of sumatriptan, a member of the triptan class of compounds with anti-migraine property. Sumatriptan succinate selectively binds to and activates serotonin 5-HT1 receptors. My opinion is NO. Unfortunately there is nothing over the counter as good as Sumatriptan/Imitrex. Unless you have cardio side effects such as high blood pressure, heart palpitations etc.