Misoprostol is a synthetic prostaglandin medication used to prevent and treat stomach and duodenal ulcers, induce labor, cause an abortion, and treat postpartum bleeding due to poor contraction of the uterus. Misoprostol is taken by mouth when used to prevent gastric ulcers in persons taking NSAIDs. For abortions it is used by itself and with mifepristone or methotrexate. Misoprostol is a synthetic prostaglandin E 1 analogue marketed as an oral preparation used to prevent and treat gastroduodenal damage induced by nonsteroidal anti-inflammatory drugs (NSAIDs). However, misoprostol is used off-label for a variety of indications in the practice of obstetrics and gynecology, including medication abortion, medical management of miscarriage, induction of labor. The Abortion Pill: Medical Abortion with Mifepristone and Misoprostol. What is the Medical Abortion? Medical Abortion (brand name Mifeprex) is a form of early abortion caused by the combination of two medications, mifepristone and misoprostol that is an option for women who are 8 weeks pregnant or less. Abortion Using Misoprostol Pills: A Guide For All Pregnant People Seeking to Self-Manage Their Abortion. Download. Download instructions for inducing abortion with misoprostol in Arabic, English, Español, Français, or Português. Globally, millions of pregnant people have safely ended their pregnancies using misoprostol. Often sold in pharmacies, misoprostol is inexpensive, easy to store and. Misoprostol may cause birth defects, abortion (sometimes incomplete), premature labor or rupture of the uterus if given to pregnant women; Safety and efficacy in patients with cardiovascular disease, diabetes, kidney (renal) impairment, or respiratory disease are not established; Use with caution in women over 35 years or heavy smokers (these patients were not included in clinical trials) Off. A medication abortion can be performed with Mifepristone and Misoprostol in succession or with Misoprostol alone. This page details information about the combination of Mifepristone and Misoprostol for an abortion with pills. If you can only access Misoprostol, please see this guide. Before starting Medication abortion can be performed with Mifepristone and Misoprostol in succession or with Misoprostol alone. This page details information about the use of Misoprostol alone for an abortion with pills. If you are able to access Mifepristone, please see this Recommended doses of Misoprostol (Cytotec®) are provided in this site along with instructions for use. WHO Clinical practice handbook for safe abortion, 2014 b) v on Hertzen et al. Lancet, 2007; Sheldon et al. 2016 FIAPAC abstract c) Gemzell-Danielsson et al. IJGO, 2007 d) Sääv et al. Human Reproduction, 2015; Kapp et al. Cochrane Database of Systematic Reviews, 2010 e) Dabash et al. For an abortion with only misoprostol, you will need to take twelve 200mcg pills of misoprostol. You’ll also want to have a painkiller on hand, like ibuprofen, to help manage pain. Acetaminophen and paracetamol do not work to manage pain during an abortion so they are not recommended. Here’s how misoprostol alone is used to end a pregnancy: Step 1: Place 4 misoprostol pills (200 mcg each. Induced Abortion (1st Trimester) 800mcg vaginally or sublingual 3-hrly (max x3 within 12 hrs) Misoprostol is best administered following an initial dose of mifepristone. If misoprostol is used alone, its effectiveness is lower, the abortion process is longer and more painful, and it is associated with higher rate of gastrointestinal side-effects. However, misoprostol, used alone, is still.