Lisinopril can be removed by hemodialysis [see CLINICAL PHARMACOLOGY ( 12.3)]. Lisinopril Description. Lisinopril is an oral long-acting angiotensin converting enzyme (ACE) inhibitor. Lisinopril, a synthetic peptide derivative, is chemically described as (S)-1-[N2-(1-carboxy-3-phenylpropyl)-L-lysyl]-L-proline dihydrate. Its empirical formula is C 21 H 31 N 3 O 5 2H 2 O and its structural. Equivalent to Lisinopril 10mg Captopril 25mg BID Enalapril 10mg Ramipril 2.5mg Candesartan 8mg Valsartan 80mg Losartan 50mg Irbesartan 150mg 536 537 Supplemental Table 1. Doses of ACE-inhibitors and ARBs equivalent to 10mg of Lisinopril 538 used to calculate the Lisinopril-dose equivalent for each subject. Reference 539 540 1. Angiotensin. Lisinopril has a drug half-life of 12 hours, equivalent to that of Lotensin (benazepril) and Vasotec (enalapril). However, the half-life is longer than drugs like Capoten (captopril), which has a half-life of fewer than three hours, or Accupril (quinapril), which has a half-life within two hours.   -If blood pressure is not controlled with lisinopril alone, a low dose of a diuretic may be added (e.g., hydrochlorothiazide, 12.5 mg). After the addition of a diuretic, it may be possible to reduce the dose of lisinopril. Usual Adult Dose for Congestive Heart Failure: Initial dose: 2.5 to 5 mg orally once a day.