The FDA's notice included the prescription drugs: esomeprazole magnesium (Nexium), dexlansoprazole (Dexilant), omeprazole (Prilosec), omeprazole and sodium bicarbonate (Zegerid), lansoprazole. Magnesium supplements often cause softening of stool. Interactions. Magnesium supplements may not be safe for people who take diuretics, heart medicines, or antibiotics. There is no known interaction between Magnesium and Nexium in our records. However, an interaction may still exist. However, an interaction may still exist. Always consult your doctor before taking these medications together. Treatment of hypomagnesemia generally requires magnesium supplements. Treatment in patients taking a PPI and who have hypomagnesemia may also require stopping the PPI. When you take Nexium or other strong acid-reducing medications, your body may not have enough stomach acid to absorb the calcium carbonate supplements. Calcium Citrate Calcium citrate can be another option for you if you take Nexium and calcium supplements. – Low magnesium levels if you take NEXIUM (for 3 months or more) – Stomach growths (fundic gland polyps), especially if you take PPIs for more than 1 year Tell your doctor about all of the medicines you take, prescription and nonprescription drugs, including clopidogrel, vitamins and herbal supplements. Magnesium is also found in many other mood-boosting supplements, often in combination with other substances, all of which are designed to promote relaxation, balanced mood, and peace of mind. 1. Magnesium is involved in hundreds of biochemical reactions in your body. magnesium salicylate ↔ esomeprazole Applies to: Choline Magnesium Trisalicylate (choline salicylate/magnesium salicylate), Nexium (esomeprazole) Coadministration with proton pump inhibitors may decrease the oral bioavailability of aspirin and other salicylates. I took magnesium oxide, which is what most magnesium supplements are. With 400 mg a day I got diarrhea. Then I read about different forms and I tried a supplement called High Absorption 100% Chelated Magnesium. It is much better absorbed, and I only have to take 200 mg a day most of the time. If I start getting cramps and take more, I still don’t get diarrhea. Magnesium is an ingredient found in many treatments for acid reflux. Antacids frequently combine magnesium hydroxide or magnesium carbonate with aluminum hydroxide or calcium carbonate. These.