There are three main ways your doctor can switch you to another antidepressant: xvii. Stop then start. This involves tapering off the first drug until it is completely out of your system, then starting the new drug. Wellbutrin is a prescription medication that is approved to treat depression. This eMedTV article explains how the medication works, highlights some of its potential side effects, offers tips on when and how to take it, and more. Comprehensive disease interaction information for Wellbutrin. Includes Bupropion - liver disease. Doctors' Answers to Frequently Asked Questions - Wellbutrin. These comments are made for the purpose of discussion and should NOT be used as recommendations for or against therapies or other treatments. Using buPROPion with alcohol may increase the risk of uncommon side effects such as seizures, hallucinations, delusions, paranoia, mood and behavioral changes, depression, suicidal thoughts, anxiety, and panic attacks. The antidepressant Wellbutrin (buproprion) is a norepinephrine-dopamine reuptake inhibitor (NDRI). It works somewhat differently than selective serotonin reuptake inhibitors (SSRIs) such as Prozac, Zoloft, and Paxil (paroxetine), and tends to not affect sexual dysfunction as much. Fluoxetine (Prozac) is an inexpensive drug used to treat mood problems such as depression, obsessive compulsive disorder, and panic attacks. It can also treat certain eating disorders. Maura's primary care physician had put her on best prozac Prozac two years earlier because she'd been feeling anxious and weepy whenever she drove on highways. BUPROPION is used to treat depression. The lowest GoodRx price for the most common version of generic Wellbutrin is around $9.00, 77% off the average retail price of $40.07. For the treatment of depression or OCD, the recommended starting Prozac dosage is 20 mg once a day. This eMedTV segment also provides dosing guidelines for bulimia and panic disorder treatment and offers tips for those taking the antidepressant.