Cymbalta ® is indicated for the treatment of: Major Depressive Disorder [see Clinical Studies ] Generalized Anxiety Disorder [see Clinical Studies ] Diabetic Peripheral Neuropathy [see Clinical Studies ] Fibromyalgia [see Clinical Studies ] Chronic Musculoskeletal Pain [see Clinical Studies ] Cymbalta Dosage and Administration Cymbalta increases the action of serotonin and norepinephrine, which are natural neurotransmitters produced by the body. This effect of Cymbalta alleviates depression and anxiety and decrease pain signals in the brain, spinal cord, and nerves. Achtung : Dies sind sehr allgemeine und nur orientierende Informationen über das Antidepressivum Duloxetin (Handelsname u.a. Cymbalta). Sie ersetzen weder die Fachinformationen der Hersteller, noch die Beratung beim Arzt oder Apotheker. Forum Stats Last Post Info; ARE YOU NEW HERE? Words from the wise about Cymbalta. The following items are based on the experiences of people posting on this board. Cymbalta, or Duloxetine is a serotonin-norepinephrine reuptake inhibitor used to treat depression and neurological pain. Find out about the uses and risks. What other drugs will affect Cymbalta? Many drugs can interact with duloxetine. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially: How to use Cymbalta. Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start using duloxetine and each time you get a refill. A person's dosage of Cymbalta is often determined by the medical condition being treated and existing medical conditions, among other things. The recommended starting dose for treating neuropathic pain or generalized anxiety disorder is 60 mg once daily. Learn about Cymbalta (Duloxetine Hcl) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Long-term users say Cymbalta works great during the first year or two. However, some have reported to suddenly noticed changes once they start reducing the intake of Cymbalta.