User Reviews for Imiquimod topical to treat Human Papilloma Virus. Also known as: Aldara, Zyclara, Zyclara Pump. The following information is NOT intended to endorse drugs or recommend therapy. But how does Aldara work? It is not exactly clear how Aldara works to treat these various conditions. However, it is thought that the beneficial effects of the drug might be due to how it activates the immune system. Does wart cream work for moles? SAVE CANCEL. already exists. Would you like to merge this question into it? MERGE CANCEL. already exists as an alternate of this question. Would you like to make it. If this does happen by accident, wash it off with warm water as soon as possible. Do not cover any treated areas with bandages or dressings. Do not cover any treated areas with bandages or dressings. As the cream begins to work, the area of skin being treated may become red, sore and swollen. Imiquimod cream (Aldara) Imiquimod cream is a cancer treatment and is also known by its brand name, Aldara. It is a treatment for: basal cell skin cancer (BCC) If the medicine does not work, you may need to use a different treatment to prevent the disease from progressing. Protect your skin from the sun. This helps reduce your risk of developing new AKs and skin cancers. User Reviews for Imiquimod topical. Also known as: Aldara, Zyclara, Zyclara Pump. The following information is NOT intended to endorse drugs or recommend therapy. Aldara cream is the only topical formulation used to treat SBCC in adults with normal immune systems. It is recommended when other methods of removal are inappropriate (such as where there are multiple lesions on the face).