Okay so my friend is a real druggie, and he's already getting help, so an intervention by me has been tried and has failed and is no longer necessary because I think he's in good hands now, but anyway, how many mg of vicodin does it take to od and die on because i really want to tell him just to make sure. show more Okay so my friend is a real druggie, and he's already getting help, so an. Vicodin is hydrocodone and paracetamol. Doses are indicated as x/y eg. 5/250, the higher number indicating the amount of paracetamol in mg and the smaller the amount of hydrocodone. Hydrocodone is to a great degree addictive. It should just be utilized when endorsed and just when expected to reduce torment. Because something is dealt with as drug does not really mean it is 'protected.' How many hydrocodone 7. 5 would it take to o. d. hydrocodone overdose by consuming maybe 7-10 pills or less. It depends on other factors like weight, age, sex, tolerance, last dosage, etc. It depends on other factors like weight, age, sex, tolerance, last dosage, etc. Hydrocodone is the narcotic element in many pain medications, but this doctor-prescribed drug comes with a risk of addiction and overdose. Seek professional help if an addiction occurs. My friend said he wants to CWE around 300 mg of hydro and take it all at once, hes not opiate nieve, he can take 30s and just have a good buzz. I believe that you might have bigger problems than hydrocodone, your liver would shut down from aspirin overdose before you would die from the hydrocodone, it would take alot. 1. Knowing how many ibuprofens does it take to die and what overdose of it can do for you is not enough, know also what to do if overdose. Call the Poison Help line (1-800-222-1222) and seek emergency medical attention. Hydrocodone and oxycodone are powerful drugs that doctors only prescribe when they are needed. The ingredients in these drugs are habit-forming, and some people may become addicted to them. If you take 2 Vicodin (or hydrocodone) pills at 5 mg each, you will not die. It does contain high levels of acetaminophen (Tylenol) which is hard on your liver with excessive use.