Ezetimibe and fatty liver

LIPTRUZET ® (ezetimibe and atorvastatin) Tablets for Oral Use. DESCRIPTION. LIPTRUZET contains ezetimibe, a selective inhibitor of intestinal cholesterol and related phytosterol absorption, and atorvastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor. Ezetimibe is a medication used to treat high blood cholesterol. It is less preferred than statins when used as sole treatment for high blood cholesterol. Nonalcoholic fatty liver disease (non-alcoholic fatty liver disease, NAFLD) is the accumulation of abnormal amounts of fat within the liver. Nonalcoholic fatty liver disease can be divided into isolated fatty liver in which there is only accumulation of fat, and nonalcoholic steatohepatitis (NASH) in which there is fat, inflammation, and damage. Vytorin is a combination of ezetimibe and simvastatin that is used for treating high levels of cholesterol in the blood. Vytorin reduces total cholesterol and low density lipoprotein (LDL or bad ) cholesterol while it increases high density lipoprotein (HDL or good ) cholesterol. Fatty liver is the accumulation of triglycerides and other fats in the liver cells. The amount of fatty acid in the liver depends on the balance between the processes of delivery and removal. In some patients, fatty liver may be accompanied by hepatic inflammation and liver cell death Introduction Atorvastatin is a commonly used cholesterol lowering agent (statin) that is associated with mild, asymptomatic and self-limited serum aminotransferase elevations during therapy and rarely with clinically apparent acute liver injury. Ezetimibe is used together with lifestyle changes (diet, weight-loss, exercise) to reduce the amount of cholesterol (a fat-like substance) and other fatty substances in the blood. Learn about the potential side effects of ezetimibe/simvastatin. Includes common and rare side effects information for consumers and healthcare professionals. Patient information for EZETIMIBE 10 MG TABLETS Including dosage instructions and possible side effects. ZETIA ® (ezetimibe) Tablet, for Oral Administration. DESCRIPTION. ZETIA (ezetimibe) is in a class of lipid-lowering compounds that selectively inhibits the intestinal absorption of cholesterol and related phytosterols.

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