CPJ/RPC • JANUARY/FEBRUARY 2011 • VOL 144, NO 1 21 Introduction Warfarin has been the mainstay of oral anticoagu-lant therapy for the past 60 years and it is most Warfarin, sold under the brand name Coumadin among others, is a medication that is used as an anticoagulant (blood thinner). It is commonly used to treat blood clots such as deep vein thrombosis and pulmonary embolism and to prevent stroke in people who have atrial fibrillation, valvular heart disease or artificial heart valves. Less commonly. Learn about Coumadin (Warfarin Sodium) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Darrell Hulisz, RPh, PharmD Associate Professor of Family Medicine Case Western Reserve University School of Medicine Associate Clinical Professor of Pharmacy Practice What are drug interactions? Anytime you take more than one medication, or even mix it with certain foods, beverages, or over-the-counter medicines, you are at risk of a drug interaction. We can next ask ourselves, what are the health care costs associated with adverse drug reactions? Again, methodological constraints limit making completely accurate estimates, but one estimate of. Warfarin is an anticoagulant used to prevent heart attacks, strokes, and blood clots. Learn about side effects, interactions and indications. CHECKING FOR POSSIBLE HERB-DRUG INTERACTIONS. by Subhuti Dharmananda, Ph.D., Director, Institute for Traditional Medicine, Portland, Oregon. The issue of herb-drug interactions looms large over the practice of herbal medicine. Find patient medical information for Warfarin Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. History. The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. The first published clinical report on grapefruit drug interactions was in 1991 in The Lancet entitled Interactions of Citrus Juices with Felodipine and Nifedipine. .