Does Hydrocodone-Acetaminophen Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or. citalopram oral and hydrocodone-ibuprofen oral citalopram oral , hydrocodone-ibuprofen oral. Either increases toxicity of the other by pharmacodynamic synergism. Other medications that can lead to Celexa drug interactions include warfarin, metoprolol, nonsteroidal anti-inflammatory drugs (NSAIDs), and cimetidine. Celexa ® ( citalopram hydrobromide) can potentially interact with a number of medicines. They are safe but they come with risks. The risks when taking Celexa and Hydrocodone include central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients. Does Celexa interact with other medications? Find Lowest Prices. Read More. Overdose. Overdose. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call. Since CBD has shown to interact with certain drugs, please speak to your doctor about this. Your doctor or pharmacist will be able to answer if there would be any problem with a drug interaction and CBD. Thanks for understanding. Even some foods can interact with drugs, so paying attention to the instructions written on the bottle, like “take with food,” or “take one hour after eating,” are important to prevent stomach upset or other food-related interactions. Since we are not licensed practitioners or doctors, so we are not legally able to answer that question. Cannabinoids like CBD may interact with prescription drugs, dietary supplements, and over-the-counter drugs. As this eMedTV page explains, drug interactions may occur if antidepressants or barbiturates are taken with hydrocodone. This article describes the potential effects of these interactions and lists other medications that may interact with hydrocodone. Identify these significant citalopram oral (Celexa Oral) drug interactions with the RxList drug interaction checker tool.