As large amounts of codeine can affect any one of the body’s major systems, treatment for codeine overdose requires emergency room staff to monitor a person’s vital signs (pulse, breathing rate, temperature and blood pressure) and treat symptoms accordingly. For all cases, the first step entails detoxification to prevent any further effects of the drug on the body. Okay, so a month ago-ish, my girlfriend's friend tried using codeine for the first time to get a high, because she'd heard that it was pretty good for a high, although it just didn't work on some people. 1) Indicated as an analgesic for the relief of mild to moderate pain. Codeine is indicated in patients older than 12 years of age for the treatment of acute moderate pain which is not considered to be relieved by other analgesics such as paracetamol or ibuprofen (alone). Codeine is indicated in patients older than 12 years of age for the treatment of acute moderate pain which is not considered to be relieved by other analgesics such as paracetamol or ibuprofen (alone). The faster someone receives treatment, the more likely he or she is to recover from a codeine overdose. However, people who experience an overdose may have a substance abuse problem. If this is the case, they should seek help at a rehab center to address possible addiction and prevent any future overdose. Codeine Overdose Treatment Remember, even non-fatal overdoses can lead to permanent injury to the human body. Medical professionals routinely have to deal with signs of brain damage, seizures, liver failure, muscle deterioration, and heart issues as a result of codeine overdoses. Codeine Overdose. A codeine overdose may occur when someone either accidentally or intentionally takes more than the normal or recommended amount of this particularly medication. Codeine overdose information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis. A codeine overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose can cause severe muscle weakness, cold and clammy skin, pinpoint pupils, very slow breathing, extreme drowsiness, or coma. Codeine overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose. This can be by accident or on purpose. This is for information only and not for use in the treatment or management of an actual overdose.