Along with its needed effects, clonidine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. I'm pretty sure my mom has hallucinations related to clonidine. Never had hallucinations until this med was started, and hallucinations worse with dose increases. Clonidine is used to manage a variety of psychiatric symptoms in addition to general medical conditions such as hypertension and pain. We report a case of auditory hallucinations in the context of clonidine use. Case report. A 53-year-old African-American man was in a motor vehicle accident that Clonidine hydrochloride is a centrally acting antihypertensive drug; its commonest adverse mental effects are sedation (1, 2) and, less frequently, depression (1, 3). Some antiarrhythmic drugs have been associated with delirium, and digitalis toxicity has been shown to cause hallucinations, mania, euphoria, and depression. The calcium-channel blocker verapamil. -also I read where mixxing klonopin and suboxone for a long time will cause hallucinations and And audible ones as well. I really think u need to fet to the hospital bc it's getting serious. Along with its needed effects, chlorthalidone/clonidine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Although not all of these side effects may occur, if they do occur they may need medical attention. Im freakin out. Im having audible hallucinations, as well as visual ones. Lots of flashing lights, but theres no place they could come from. Im in day 6, its worse than i ever expected. -also I read where mixxing klonopin and suboxone for a long time will cause hallucinations and And audible ones as well. I really think u need to fet to the hospital bc it's getting serious. Not only r u messing with ur health u r also messing with ur mental health. The manufacturer's product labeling should always be consulted for a list of side effects most frequently appearing in patients during clinical studies.