I get this question a lot: Is it safe to take acetaminophen with ibuprofen? The simple answer? Yes, you can safely take acetaminophen and ibuprofen together. Actually both the responses are correct. These two can be taken together, and Tylenol does not recommend taking them together. You can indeed take both of these medications at the same time, and in fact your doctor may recommend that you do so. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Jacobs on can i take tylenol and diclofenac: But not on a regular basis. And as long as you don't have severe liver or kidney disease. You can take meloxicam and Tylenol together but I would not recommend that you take meloxicam and Aleve together. You can take both together, as they both perform different functions. There should be no side effects, given you have no side effects from either individually. Interactions between your selected drugs No results found - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Le on is it okay to take advil and percocet together: This combination may be very effective on a short-term basis, such as treating pain due to surgery or fracture. Yes, as long as there are no allergies for u to the meds, it should be fine to take together. Benadryl is an antihistamine and tends to have a drying effect on mucus membranes, also. Yes, you can take Tylenol and aleve together. Aleve is in a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). Although Tylenol is also used to reduce fever and relieve pain, it is in its very own class of drug which has a completely different mechanism of action;therefore, they can be safely used together. It is Advil liquid gel 200 (would be taking 3 tablets total) and Tylenol rapid release (2 tablets) both at the same time. Probably would not repeat the dose until the following day, only if needed.