I read that you should never take an L-Tyrosine supplement when you're taking thyroid medication. It was like a had a beacon of hope for exactly five minutes before it all came crashing down. It was like a had a beacon of hope for exactly five minutes before it all came crashing down. Typically, if you walk into a health food store and you speak with a store clerk or the manager about supplements you could benefit from in you have hypothyroidism, they will often recommend iodine and tyrosine (also known as L-tyrosine). If you take their advice you may be making a big mistake. She only told me not to take vitamins with the levothyroxine.I also have a sinus and allergy problem beside the thyroid and acid.I also take sudifed in the morning, birth control and L-TYROSINE 500mgs. I know before medication there alot of supplements out there you can take to hopefully treat hypothyroidism, but I always forget or get confused what supplements you can take and will benefit from after you are on synthroid L-tyrosine--will benefit or not matter once on medication Evening primrose?? Summary. Drug interactions are reported only by a few people who take L-tyrosine and Synthroid together. This review analyzes the effectiveness and drug interactions between L-tyrosine and Synthroid. What, if any, interactions or affects can I expect if I also take Acetyl-L Tyrosine 300mg per day? The Synthroid, of course, is for hypothyroidism. I want to try Tyrosine to boost my energy and mood levels, but I understand that Tyrosine may affect the thyroid gland. Unless you have had a thyroid problem or are in a medical profession you most likely have not heard of L-tyrosine. In this article we are going to discuss what it is, how it works, benefits, the dosage and more, particularly how it interacts with the thyroid. If you are already taking prescription thyroid medications, taking additional L-Tyrosine supplements can interfere with their action. Before adding L-Tyrosine supplements to medications such as Levothroid , Unithroid , Synthroid , or Levoxyl consult with your physician. Also, do not take L-tyrosine along with prescribed thyroid hormone drugs, unless your doctor advises it. L-tyrosine can cause digestion trouble and migraine headaches, UMMC states. Do not use tyrosine to replace medical treatment for your thyroid disorder, and discuss the use of tyrosine with your doctor. I hada total thyroidectomy in August. I am taking 112 mg of synthroid and also take L-tyrosine with my synthroid in the morning. Does anyone know if the L-tyrosine still aid with the synthroid even without a thyroid.