CELEBREX U.S. Medical Information Page - clinical & safety information, ways to contact Pfizer Medical & other resources Visit See related articles Celecoxib, sold under the brand name Celebrex among others, is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis. It may also be used to decrease the risk of colorectal adenomas in people. CELEBREX can cause serious side effects, including: new or worse high blood pressure; heart failure; liver problems including liver failure; kidney problems including kidney failure; low red blood cells (anemia) life-threatening allergic reactions; life-threatening skin reactions; Other side effects of NSAIDs, including CELEBREX, are stomach pain, constipation, diarrhea, gas, heartburn, nausea. These serious adverse events can occur at any time, with or without warning symptoms, in patients treated with CELEBREX. Only one in five patients who develop a serious upper GI adverse event on NSAID therapy is symptomatic. Upper GI ulcers, gross bleeding, or perforation caused by NSAIDs occurred in approximately 1% of patients treated for 3 to 6 months, and in about 2% to 4% of patients. For Celebrex, the FDA requests this medication have a black box warning due to the increased risk of cardiovascular events, along with an increased risk of gastrointestinal bleeding. These side effects are possible with any NSAID. Celecoxib (Celebrex) is a moderately priced drug used to treat arthritis and ankylosing spondylitis. It may also be used for pain or painful monthly periods. This drug is slightly more popular than comparable drugs. It is available in brand and generic form. Generic celecoxib is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Find patient medical information for Celebrex oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. CELEBREX can cause serious side effects, including: new or worse high blood pressure; heart failure; liver problems including liver failure; kidney problems including kidney failure; low red blood cells (anemia) life-threatening allergic reactions; life-threatening skin reactions; Other side effects of NSAIDs, including CELEBREX, are stomach pain, constipation, diarrhea, gas, heartburn, nausea. Celebrex is used to treat juvenile rheumatoid arthritis in children who are at least 2 years old. It is also used in the treatment of hereditary polyps in the colon. Warnings. Celebrex may cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older. Celebrex can also make your skin more sensitive to sunlight, so you should protect your skin from the sun while taking it. Keep in mind that Celebrex can cause more serious skin reactions that, in.