How to use Celebrex. Read the Medication Guide provided by your pharmacist before you start using celecoxib and each time you get a refill. If you have any questions, ask your doctor or pharmacist. What Celebrex is used for? Celebrex reduces certain hormones in human body. The drug affects only hormones causing pain and inflammation. One may want to buy Celebrex to get rid of inflammation or pain that occurred due to such conditions as ankylosing spondylitis, arthritis or menstrual periods in women. Newly developed drugs that selectively block the COX-2 enzyme are called COX-2 inhibitors. Blocking this enzyme impedes the production of the prostaglandins that cause the pain and swelling of arthritis inflammation. CELEBREX is used to treat pain and redness, swelling, and heat (inflammation) from osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis in patients 2 years and older, and ankylosing spondylitis; and for the management of acute pain in adults, and for the management of menstrual cramps. Celebrex (celecoxib) is the only COX-2 selective NSAID currently on the market in the United States. COX-2 selective NSAIDs are considered less likely to cause stomach problems than traditional NSAIDs – popular medications used to treat arthritis. Easy Health Options Home » Health Conditions » Prescription Drugs » The arthritis drug that makes your heart old and tired. The arthritis drug that makes your heart old and tired Voltaren (diclofenac) and Celebrex (celecoxib) are nonsteroidal anti-inflammatory drugs (NSAIDs) used to treat pain, fever, and inflammation caused by conditions such as rheumatoid arthritis and osteoarthritis. Voltaren is also used to treat pain, fever, and inflammation caused by ankylosing User Reviews for Celebrex to treat Rheumatoid Arthritis. The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Celebrex is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. Celebrex is used to treat pain or inflammation caused by many conditions such as arthritis, ankylosing spondylitis, and menstrual pain. One of the reasons Vioxx and Celebrex were developed was to create drugs that wouldn’t be as hard on the digestive system as standard pain relievers, which can lead to ulcers and to bleeding.