Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Ketamine is a medication mainly used for starting and maintaining anesthesia. It induces a trance-like state while providing pain relief, sedation, and memory loss. Other uses include for chronic pain, sedation in intensive care, and depression. Two medicines that can help thin mucus are guaifenesin and SSKI. These are minimally effective for most people but work well for others and are worth a try. This site uses cookies. By continuing to browse the site you are agreeing to our policy on the use of cookies. Continue.