Betamethasone is a steroid medication. It is used for a number of diseases including rheumatic disorders such as rheumatoid arthritis and systemic lupus erythematosus, skin diseases such as dermatitis and psoriasis, allergic conditions such as asthma and angioedema, preterm labor to speed the development of the baby's lungs, Crohn's disease. Hydrocortisone and betamethasone are examples of low- and high-potency topical corticosteroids. Topical corticosteroids have been ranked in terms of potency into four groups consisting of seven classes. Topical Corticosteroids. Tier-1 products are covered with no prior authorization necessary. Tier-2 Topical Corticosteroid Approval Criteria: Documented trials of all Tier-1 topical corticosteroids of similar potency in the past 30 days that did not yield adequate relief; AND Betamethasone is a glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Adverse effects. Although the absorption of betamethasone dipropionate is small, when used for prolonged periods of time (periods exceeding two weeks), or across a large surface area (total use greater than 50 grams per week), it can have adverse effects. CELESTONE ® SOLUSPAN ® (betamethasone sodium phosphate and betamethasone acetate) Injectable Suspension, USP. DESCRIPTION. CELESTONE ® SOLUSPAN ® Injectable Suspension is a sterile aqueous suspension containing 3 mg per milliliter betamethasone, as betamethasone sodium phosphate, and 3 mg per milliliter betamethasone acetate. Medicines are used to treat diseases, manage conditions, and relieve symptoms. Medicines are generally safe when used as prescribed or as directed on the label, but there are risks in taking any medicine. BetaVet ® (betamethasone sodium phosphate and betamethasone acetate injectable suspension) INDICATION: BetaVet ® (betamethasone sodium phosphate and betamethasone acetate injectable suspension) is indicated for the control of pain and inflammation associated with osteoarthritis in horses. Betamethasone Pharmacokinetics Absorption Bioavailability. Following intra-articular administration, systemic absorption of the soluble portion (betamethasone sodium phosphate) of the injectable suspension is rapid. Betamethasone Sodium Phosphate and Betamethasone Acetate Injectable Suspension is a sterile aqueous suspension containing 3 mg per milliliter betamethasone, as betamethasone sodium phosphate, and 3 mg per milliliter betamethasone acetate.