Healthcare providers consider acetaminophen (Tylenol) the safest over-the-counter pain reliever and fever reducer to take when you're pregnant. Acetaminophen has been widely used for decades, and extensive research shows that it's safe to take during pregnancy. yes it is safe to take Tylenol during pregnancy, its the only thing you can take. I take 2 500mg's when my pain gets real bad but I try not to do it that often. I take 2 500mg's when my pain gets real bad but I try not to do it that often. Active ingredient Acetaminophen 500 mg (in each caplet) Purpose Pain reliever/fever reducer. Inactive ingredients carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate. Like most other medications, Tylenol or acetaminophen should only be used when indicated and according to instructions. Pregnancy There is no increased risk of miscarriage or fetal/maternal death associated with using the medication according to package instructions. TYLENOL 500 TYLENOL 500 (Tylenol Extra Strength 500 mg) Generic Name: acetaminophen Pill with imprint TYLENOL 500 TYLENOL 500 is Yellow / Red, Capsule-shape and has been identified as Tylenol Extra Strength 500 mg. Risk cannot be ruled out during pregnancy. Tylenol Extra Strength 500 mg is not a controlled substance under the Controlled Substances Act (CSA). Tylenol Extra Strength 500 mg is not a controlled substance under the Controlled Substances Act (CSA). TYLENOL® Extra Strength Coated Tablets for Adults should be used to temporarily reduce fever and relieve minor aches and pains. Each extra-strength pain relief coated tablet contains 500 milligrams of acetaminophen and can be a safe and effective post-surgery pain relief option when used as directed. There are so many do's and don'ts when it comes to pregnancy. Don't eat this, do eat that, don't do this, do this. I recently went to an OB appointment for a prenatal visit (sadly, I miscarried later on) and I was shocked by how much has changed since I had my first baby 10 years ago. Is Tylenol (acetaminophen) safe during pregnancy? Occasional use of Tylenol (generic name acetaminophen and paracetamol) is usually considered safer than other similar medications and NSAIDS for treating minor fever, cold, flu and sinus. If you have pain during pregnancy, you may take Tylenol or acetaminophen up to 2 tablets or 650 mg every 4 hours. Do not take aspirin during your pregnancy unless instructed to do so by your physician.