I am currently taking 12.5 mg of Trazodone and 5 mg of Lexapro while pregnant (I'm 17 weeks). Unfortunately, I suffer from insomnia, depression and anxiety and my doctor recommended I continue taking the meds throughout the pregnancy to avoid stress to myself and the baby. Q&A: Can taking antidepressants affect fertility? - Find out if taking antidepressants to treat depression while trying to conceive could have a positive or negative impact on your fertility chances. Learn more about your fertility at TheBump.com. Yes, the safety of Trazodone use during pregnancy is uncertain. Generally you should wait for at least one month after stopping Trazodone before trying to get pregnant. Forgive me for posting this here, I also posted it in the depression board. Long story short, my daughter was stillborn in September. DH & I are trying to conceive again. Re: Trazodone, Trying to Conceive & Pregnancy Oh, wow, thanks so much for the information! I stopped taking trazodone in the two weeks before conception, and within 7 days of implantation, so I'm pretty sure that I'm safe. Effects While Trying to Conceive: The effects of Celexa on fertility has been tested in animal studies, but not in human studies. In animal studies doses in excess of 5 times the maximum recommended human dose (MRHD) caused fertility problems and doses in excess of 8 times the MRHD caused prolonged gestation. If the male partner takes antidepressants and you have not been able to get pregnant despite trying for a long time, there could be a link between these two. However, you don’t have to worry that much because the research has also pointed out that the effects on the sperm are not permanent. I am 29 year old female trying to conceive for the first time with my husband. I have been on birth control since I was 18, and just went off a few days ago. Recently, my husband and I are thinking about trying for a baby. I told my doctor this and he told me to let him know when we decide because he will take me off of the trazodone. He wants to make sure that the medication is out of my system before I conceive. My husband and I are now trying to get pregnant and my OB says no to Trazodone. I have gone off of it and gone back to my horrible insomnia of 2-3 hours of sleep a night. I can’t live like this – I can’t take care of myself properly in this state and can’t imagine nurturing a baby in my womb when I am like this. But over the counter sleep medication (Tylenol PM, Unisom, Benadryl.