What's tops in, topical steroid treatments? How do they work, which is right for you, and what is your doctor talking about? The National Psoriasis Foundation did the research and interviewed health care providers and people with psoriasis to give you all the answers, all in one place! Clobetasol Propionate is a topical steroid ointment that is used to treat various auto-immune and skin conditions, such as: • Severe eczema • Anogenital pruritus (genital and anal itch) WARNING Clobetasol propionate is a very strong topical corticosteroid that causes serious side effects if absorbed into the blood. If absorbed into the blood stream prolonged use of clobetasol can depress the ability of the body's adrenal glands to produce corticosteroids. User Reviews for Clobetasol topical to treat Psoriasis. Also known as: Clobex, Clodan, Cormax, Olux, Olux-E, Temovate.show all 13 brand namesTemovate E, Embeline E, Clobevate, Embeline, Olux/Olux-E Kit, Cormax Scalp, Impoyz Pictures of Clobex Spray (Clobetasol Propionate Spray), drug imprint information, side effects for the patient. DESCRIPTION. Topical, synthetic fluorinated corticosteroid Used for moderate-severe corticosteroid-responsive dermatoses, including psoriasis One of the most potent topical corticosteroids; recommended for short-term / cyclic treatment Clobetasol propionate is a corticosteroid of the glucocorticoid class used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/oak. INDICATIONS Indication. CLOBEX ® Spray, 0.05% is a super-high potent topical corticosteroid formulation indicated for the treatment of moderate to severe plaque psoriasis affecting up to 20% body surface area in patients 18 years of age or older. i use Clobetasol Propionate 0.05% for scalp and skin and FLUOCINONIDE TOPICAL SOLUTION USP, 0.05%(this just for scalp psoriasis). i was wondering how long these ingredients stay active. for example i apply these normally like an hour before bed and i wonder if the ingredients could still be active and rub from my scalp to my pillow, then to my. Clobetasol Propionate reference guide for safe and effective use from the American Society of Health-System Pharmacists (AHFS DI).