Management of Women with Bleeding Irregularities While Using Contraception * If bleeding persists, or if woman requests it, medical treatment can be considered 2 Medroxyprogesterone acetate, administered parenterally in the recommended doses to women with adequate endogenous estrogen, transforms proliferative endometrium into Doctors help you with trusted information about Spotting in Perimenopause: Dr. Killian on perimenopause spotting instead of period: An irregular period can be a sign of pregnancy. Take a home pregnancy test if you are concerned. Medroxyprogesterone acetate (MPA), also known as depot medroxyprogesterone acetate (DMPA) and sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type. Medroxyprogesterone injection may decrease the amount of calcium stored in your bones. The longer you use this medication, the more the amount of calcium in your bones may decrease. DESCRIPTION. PROVERA® tablets contain medroxyprogesterone acetate, which is a derivative of progesterone. It is a white to off-white, odorless crystalline powder, stable in air, melting between 200 and 210°C. Medroxyprogesterone is a progestin (a form of progesterone), a female hormone that helps regulate ovulation (the release of an egg from an ovary) and menstrual periods. Hi foor, Medroxyprogesterone is not a form of birth control,as you said it was prescribed to regulate your cycles and it is also used for absent periods or to help you ovulate properly. Find a comprehensive guide to possible side effects including common and rare side effects when taking Provera (Medroxyprogesterone Acetate Tablets) for healthcare professionals and consumers. Depo-Provera is the brand name of the drug medroxyprogesterone, which is an injection used to prevent pregnancy. A form of this medication may also be used to treat endometriosis (a condition.