Common side effects of Celebrex include: diarrhea, hypertension, and abnormal hepatic function tests. Other side effects include: abdominal pain, dyspepsia, gastroesophageal reflux disease, peripheral edema, vomiting, and increased liver enzymes. Celebrex has been studied extensively in clinical trials. In these studies, side effects occurring in a group of people taking the drug are documented and compared to those that occur in another group taking a placebo (a sugar pill with no active ingredient). In a small number of patients with a history of ulcer disease, the complicated and symptomatic ulcer rates in patients taking CELEBREX alone or CELEBREX with ASA were, respectively, 2.56% (n=243) and 6.85% (n=91) at 48 weeks. Find a comprehensive guide to possible side effects including common and rare side effects when taking Celebrex (Celecoxib) for healthcare professionals and consumers. Before you take CELEBREX, inform your healthcare provider of any medical conditions you may have and of all of the medications you take, including prescription or over-the-counter medicines, vitamins, or herbal supplements as they may increase the risk for serious side effects. Q: I have been taking Celebrex for 9 months with no side effects. However, I recently have noticed a skin irritation similar to a bad sunburn where my skin is red and flaking off. I do not want to. Stop taking celecoxib and get medical help right away if you notice any of the following rare but serious side effects: bloody or black/tarry stools, persistent stomach/abdominal pain, vomit that. Celebrex side effects Get emergency medical help if you have signs of an allergic reaction to Celebrex ( hives , difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat , burning eyes, skin pain, red or purple skin rash with blistering and peeling). Find information about common, infrequent and rare side effects of Celebrex Oral. Celebrex side effects are generally not life-threatening, but may in rare cases be serious. If you believe you are having an allergic reaction to any medication, seek immediate medical help. If you have any questions about the benefits or side effects of any medication, always talk to your doctor. They are your best resource for helping you live your healthiest life.