Ive been on Prednisone steroid for about 2 months and ive been taking 80 mg. I have really bad moon face and ive gained like 15 pounds. Ive began to taper down on the meds, 10 mg every six days, when will my moon face go away? And do i lose the pounds ive gained from the medicine? Prednisone is a prescribed medication that reduces swelling, irritation, and inflammation in the body for a range of conditions. While this powerful steroid drug is helpful for many, it also packs. Prednisone oral tablet is available as a generic drug and a brand-name drug. Brand name: Rayos. Prednisone comes as an immediate-release tablet, a delayed-release tablet, and a liquid solution. Side Effects. Nausea, vomiting, loss of appetite, heartburn, trouble sleeping, increased sweating, or acne may occur. If any of these effects persist or worsen, tell your doctor or pharmacist. Side Effects. Drug information provided by: IBM Micromedex. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Prednisone is a corticosteroid. It prevents the release of substances in the body that cause inflammation. It also suppresses the immune system. The long-term effects of prednisone can often be severe and irreversible, leading to an increased risk of osteoporosis (bone loss), cataracts (clouding of the eyes), and the development of diabetes. Prednisone Side Effects. It is common for doctors to prescribe Prednisone in cases of inflammation, allergies and such skin issues. Then again, every drug you consume has some unwanted effects along with the desired effects. Learn about the potential side effects of prednisone. Includes common and rare side effects information for consumers and healthcare professionals. Prednisone (Prednisone Intensol, Rayos) is a drug used for suppressing the immune system and inflammation such as asthma, severe psoriasis, lupus, ulcerative colitis, Crohn's disease, and several types of arthritis. Side effects, drug interactions, dosage, and pregnancy and breastfeeding safety information are provided.