Medical uses. Oxycodone is used for managing moderate to severe acute or chronic pain when other treatments are not sufficient. It may improve quality of life in certain types of pain. It is unclear if use in chronic pain results in improved quality of life or ongoing pain relief. ROXICODONE (oxycodone hydrochloride) Tablets USP. DESCRIPTION. ROXICODONE® (oxycodone hydrochloride tablets USP) is an opioid analgesic. Each tablet for oral administration contains 5 mg, 15 mg or 30 mg of oxycodone hydrochloride USP. Each ml contains oxycodone hydrochloride 10 mg (equivalent to 9 mg of oxycodone base). Each 1 ml ampoule contains oxycodone hydrochloride 10 mg (equivalent to 9 mg of oxycodone base). 5 mg tablet contains 4.5 mg of oxycodone as 5 mg of oxycodone hydrochloride. 10 mg tablet contains 9.0 mg of oxycodone as 10 mg of oxycodone hydrochloride Oxycodone reference guide for safe and effective use from the American Society of Health-System Pharmacists (AHFS DI). Oxycodone Hydrochloride and Acetaminophen Tablets contain acetaminophen, 4'-hydroxyacetanilide, is a non-opiate, non-salicylate analgesic and antipyretic which occurs as a white, odorless, crystalline powder. Oxycodone is an opioid agonist and therefore has abuse potential and risk of fatal overdose from respiratory failure. Addiction may occur in patients who obtain oxycodone illicitly or in those appropriately prescribed the drug. Generic Products. Generic drug products allow for more accessibility to healthcare options for all Americans. These drugs are equivalent to brand name drugs in dosage form, strength, route of administration, quality, performance characteristics and intended use. Contains Nonbinding Recommendations Draft Guidance on Oxycodone HCl. Recommended Jul 2010; Revised Oct 2016; Jul 2018. This draft guidance, when finalized, will represent the current thinking of. Detailed Oxycodone dosage information for adults and children. Includes dosages for Pain and Chronic Pain; plus renal, liver and dialysis adjustments.