Correct; a peculiar cross reaction with a specific food exists with Lipitor and other statin drugs used to lower cholesterol. Grapefruit juice blocks special enzymes in the wall of the small intestine that actually destroy many medications, including Lipitor, and prevents their absorption into the body. When mixing grapefruit and statins, there is a chance of increased side effects. Women and people over 65 are at a higher risk of developing side effects from statins. Grapefruit (Citrus paradisi) is nutritious fruit full of vitamin C, antioxidants, and a tangy-sweet flavor. However, research points to hundreds of drug interactions -- many of which may be serious -- with grapefruit. Do Your Statins and Grapefruit Safely Mix? Do you take statin medications to lower “bad” LDL cholesterol? Eating grapefruit while taking these drugs can increase the risk of side effects. There is a popular assumption that grapefruit may be safe if eaten before or after a dose of Lipitor, Mevacor, or Zocor. At present, no one really knows where the safe line is. At present, no one really knows where the safe line is. One of those things that are surprising is that you should not mix grapefruit and statins. Most of us love this juicy fruit, especi Most of us love this juicy fruit, especi Grapefruit contains a certain chemical called furanocoumarin that blocks the absorption of statins in the liver. Statins and grapefruit WARNING: Mixing drugs and fruit could be DEADLY cocktail STATINS - drugs to reduce cholesterol - are prescribed to millions of people in the UK, but experts reveal the. What's more, eating half a grapefruit is even less risky than drinking grapefruit juice, since it takes several fruits to make a single glass of juice. But to be on the safe side, check with your doctor, and avoid taking your pills with grapefruit juice. Grapefruit juice and the actual grapefruit can be part of a healthy diet. Grapefruit has vitamin C and potassium—nutrients your body needs to work properly. But it isn’t good for you when it.