Methotrexate is one of the most effective and widely used medications for treating rheumatoid arthritis (RA) and other inflammatory types of arthritis. If you have rheumatoid arthritis (RA), you’re probably very familiar with the pain and joint swelling that this particular type of arthritis can cause. Rheumatoid arthritis (RA) is an inflammatory disease of the joints in areas like the hands, feet or wrist. The joints become painful, stiff, and tender and may feel warm or look red. Rheumatoid arthritis treatment options include medications, reduction of joint stress, physical and occupational therapy, and surgical intervention. Methotrexate is one of the most effective medications to treat rheumatoid arthritis (RA). It's the first drug most doctors prescribe after you’re diagnosed. It will help ease symptoms like joint. Rheumatoid arthritis is a chronic autoimmune disease characterized by inflammation and by joint destruction that leads to substantial disability. Rheumatoid arthritis natural treatment, herbs vitamins supplements diet, alternative therapy October 8 2018 by Ray Sahelian, M.D. Rheumatoid arthritis is an autoimmune disease in which joints, usually those of the hands and feet, are symmetrically inflamed, resulting in swelling, pain, and often the eventual destruction of the joint's interior. Methotrexate (brand name Methoblastin) is a medicine used to treat rheumatoid arthritis as well as other rheumatic conditions such as juvenile arthritis, lupus (also known as SLE), psoriatic arthritis and polymyositis (muscle inflammation). Methotrexate is an immunosuppressive medicine, and reduces inflammation in the joints and associated pain. Methotrexate is an antimetabolite used in the treatment of certain neoplastic diseases, severe psoriasis, and adult rheumatoid arthritis. Chemically methotrexate is L-(+)-N-[p-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]-benzoyl]glutamic acid. Methotrexate is one of the most effective and commonly used medications in the treatment of rheumatoid arthritis and other forms of inflammatory arthritis, and also may be used to treat lupus, inflammatory myositis, vasculitis, and some forms of childhood arthritis.