or 6-mercaptopurine to treat patients with Crohn’s disease (strong recommendation, low level of evidence). 23 Methotrexate (up to 25 mg once weekly IM or SC) is effective and should be considered for use in alleviating signs and symptoms in patients with steroid-dependent Crohn’s disease and for maintaining remission (conditional recommendation, low level of evidence). 24 Anti-TNF agents. Pediatric Drugs. Mercaptopurine (also referred to as 6-mercaptopurine or 6-MP) is a purine analogue that is effective both as an anticancer and an immunosuppressive agent, and is used to treat leukemia and autoimmune diseases as a corticosteroid-sparing agent. Mercaptopurine therapy is associated with a high rate of serum aminotransferase elevations which can be accompanied by jaundice. Crohn's and Colitis UK has more about azathioprine and mercaptopurine. Biological medicines. If other medicines are not helping, stronger medicines called biological medicines may be needed. The biological medicines for Crohn's disease are adalimumab, infliximab, vedolizumab and ustekinumab. Biological medicines: can relieve symptoms if other medicines are not working; can be used as a long. If you’ve been prescribed azathioprine or mercaptopurine, or are considering it as an option, you’re not alone. These medicines are a common treatment for Crohn's Disease and Ulcerative Colitis, with around 6 out of 10 people with the conditions taking them at some point. Our information can support you to make an informed decision about this treatment that’s right for you. It looks at. Mercaptopurine (6-MP), sold under the brand name Purinethol among others, is a medication used for cancer and autoimmune diseases. Specifically it is used to treat acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn's disease, and ulcerative colitis. For acute lymphocytic leukemia it is generally used with methotrexate. It is taken by mouth. mercaptopurine monohydrate meropenem trihydrate mesalazine mesna mestranol metaraminol tartrate metformin hydrochloride methadone hydrochloride methenamine hippurate methionine methocarbamol methotrexate methotrexate disodium methotrexate sodium methoxy polyethylene glycol-epoetin beta. Acute lymphoblastic leukemia (ALL) is a type of blood cancer. Learn more about the causes, risk factors, symptoms, diagnosis, treatment types, and prognosis for acute lymphoblastic leukemia. mercaptopurine may be dangerous if it gets in your eyes or on your skin. If this occurs, wash your skin with soap and water or rinse your eyes with water. Seek medical attention if you have redness, itching, or swelling even after rinsing off the medicine. Mercaptopurine. Both valproate and mercaptopurine can increase the risk of hepatotoxicity. Meropenem. Meropenem decreases the concentration of valproate. Manufacturer advises avoid. Severity of interaction: Severe Evidence for interaction: Anecdotal. Methotrexate. Both valproate and methotrexate can increase the risk of hepatotoxicity. Micafungin. Both valproate and micafungin can increase the.