Call your doctor right away if you get a headache, stomach pain, vomiting, dark-colored urine, loss of appetite, weight loss, general feeling of tiredness or weakness, light-colored stools, upper right stomach pain, or yellow eyes or skin. These could be symptoms of liver damage. Statin medications include the well-known drugs atorvastatin, or Lipitor, simvastatin, or Zocor, lovastatin, or Mevacor, pravastatin, or Pravachol and rosuvastatin, or Crestor. Like all medications, statins have side effects and may affect your weight. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Foreman on does lipitor cause weight loss: Weight loss is not one of the mentioned side effects of atorvastatin. Weight loss as a side effect of any cholesterol medication is a rare, but possible. Statins may contribute to interstitial lung disease, according to PubMed.gov. Overtime this condition can result in weight loss. Then I started low carbing and losing weight and was eventually taken off the lipitor completely. Obviously it works for some people and not for others. I hope that you are one. Obviously it works for some people and not for others. He is 67 and has increasing fatigue, weight loss and muscle tone decline. He is able to work (farmer) but is increasinly fatigued. I want him to stop the Lipitor. It causes loss of appetite, therefore it will cause weight loss. Loss of appetite is a serious side effect , you must stop using the medication and contact your doctor ASAP. But lc and weight loss led my doctor to take me off of the Lipitor this past June, and I haven't seen any more rapid weight loss since then, just the same pattern. Lipitor has appetite loss listed as a potential side effect, this would, naturally, cause weight loss. If you have appetite loss please consult your physician since it is a potentially major side effect.