Compare Lialda vs. Mesalamine, which is better for uses like: Ulcerative Colitis, Crohn's Disease and Colitis. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Lialda 3/5 over Mesalamine 2.8/5 in overall satisfaction. Apriso, Asacol, Asacol HD, Canasa, Canasa Pac, Delzicol, Lialda, Pentasa, Rowasa, Rowasa Sulfite Free, Zaldyon View more Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. Compare Lialda vs. Pentasa, which is better for uses like: Ulcerative Colitis, Crohn's Disease and Colitis. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Lialda 3/5 over Pentasa 2.8/5 in overall satisfaction. Has anyone tried Lialda? Does it perform any better than Asacol? How much more is your co-pay for Lialda than Asacol. I want to ask my doc to make a switch. I haven't noticed a difference between asacol and lialda, other than lialda being much easier to take due to only having to take it once day. Also the Lialda pills are huge. Think horse pills. Compare Asacol vs Lialda head-to-head for uses, ratings, cost, side effects, interactions and more. Asacol rated 7.0/10 vs Lialda rated 7.3/10 in overall patient satisfaction. Has anyone tried Lialda? Does it perform any better than Asacol? How much more is your co-pay for Lialda than Asacol. I want to ask my doc to make a switch. Apriso does have less mesalamine than Asacol and Lialda, but it's forumlated to dissolve so differently that it theoretically is more effective at dispersing the mesalamine in the colon. Mesalamine (Lialda) is an expensive drug used to treat the pain and inflammation caused by ulcerative colitis. This drug is more popular than comparable drugs. Has anyone tried Lialda? Does it perform any better than Asacol? How much more is your co-pay for Lialda than Asacol. I want to ask my doc to make a switch.