Before taking this medicine. You should not use this medicine if you are allergic to levofloxacin or other fluoroquinolones (ciprofloxacin, gemifloxacin, moxifloxacin, norfloxacin, ofloxacin, and others). Levofloxacin solution is administered by slow intravenous infusion once or twice daily. The dosage depends in the type and severity of the infection and the susceptibility of the presumed causative pathogen. MEDICATION GUIDE LEVAQUIN ® [Leave ah kwin] (levofloxacin) 250 mg Tablets, 500 mg Tablets, and 750 mg Tablets And LEVAQUIN ® (levofloxacin) Oral Solution, 25 mg/mL Avoid use of systemic quinolones, such as levofloxacin, in patients with a history of myasthenia gravis. Systemic quinolones may exacerbate the signs of myasthenia gravis and lead to life threatening weakness of the respiratory muscles. DEA U.S. Drug Enforcement Administration and Pharmacy. The DEA is a branch of the U.S. Department of Justice. Their mission is to enforce the Controlled Substances Act. Levofloxacin injection is indicated for the treatment of adults (≥ 18 years of age) with mild, moderate, and severe infections caused by susceptible isolates of the designated microorganisms in the conditions listed in this section. Drug Information on Levaquin, Levaquin Leva-Pak (levofloxacin (oral)) includes drug pictures, side effects, drug interactions, directions for use, symptoms of overdose, and what to avoid. Academia.edu is a platform for academics to share research papers. DESCRIPTION. LEVAQUIN ® Tablets are synthetic antibacterial agents for oral administration. Chemically, levofloxacin, a chiral fluorinated carboxyquinolone, is the pure (-)-(S)-enantiomer of the racemic drug substance ofloxacin. Medscape - Infection dosing for Levaquin, Levofloxacin Systemic (levofloxacin), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.