Emotional dysregulation (ED) is a term used in the mental health community to refer to an emotional response that is poorly modulated, and does not fall within the conventionally accepted range of emotive response. Always evaluate patients with mania, hypomania, or mixed episode, and those with bipolar depression, for suicidality, acute or chronic psychosis, or other unstable or dangerous conditions. I'm on Cymbalta 30mg and Abilify 5mg, and while this barely gets me by, I was looking for something that would give me some energy and motivation. Here are a few details for some of the not-obvious treatment components above. One approach that is crucial for most patients with bipolar disorder is to maintain a regular daily schedule, especially regular patterns of sleep. INTRODUCTION — Patients with intermittent explosive disorder are periodically unable to restrain impulses that result in verbal or physical aggression. The aggressive behaviors are unplanned, out of proportion to the provocation, and cause subjective distress or psychosocial impairment. Strokes are caused by a disruption of blood flow to your brain. Without blood and nutrients, your brain tissue quickly begins to die, which can have lasting effects. Anhedonia is a diverse array of deficits in hedonic function, including reduced motivation or ability to experience pleasure. While earlier definitions of anhedonia emphasized the inability to experience pleasure, anhedonia is used by researchers to refer to reduced motivation, reduced anticipatory pleasure (wanting), reduced consummatory. Seroquel (quetiapine): I’ve had many problems with the wrong medications making me more unstable including restlessness. My seroquel dose was raised very quickly to 250mg in hospital, then overmedicated after. A one-stop shop, covering everything a doctor, teacher or trainee will ever need to know about neuropsychopharmacology. Pharmacology Self-Study Manual for Nurses 2012 Prepared by: Jerry Harris, MSN, RN, CNS Approved by: Statewide Nursing Leadership Committee & Division Medical Executive Committee.