Is Prenatal Dexamethasone Safe? Probably not. Administering synthetic steroids during critical periods of fetal development- when physiological systems are organizing and developing – will impact system and organ functioning. Can I take dexamethasone while pregnant or breastfeeding? Find out if it's safe to take this steroid during pregnancy and if it gets into breast milk Dexamethasone and Pregnancy Based on both animal studies and observational studies, the Food and Drug Administration considers dexamethasone a pregnancy Category C medication. Some sources also consider it a pregnancy Category D drug if used during the first trimester. Dexamethasone has been assigned to pregnancy category C by the FDA. This means that animal studies have shown problems and there are no human studies. My gynae has now suggested that i take a dexamethasone injection to help my baby's lungs develop better in case of premature birth again however i have been reading on the internet that this shouldn't be used during pregnancy. Can you please clarify whether this injection is harmful or useful to my unborn child. Can I take Dexamethasone while breastfeeding? Because no information is available on the use of systemic dexamethasone during breastfeeding, an alternate corticosteroid may be preferred, especially while nursing a newborn or preterm infant. When Susan Manning, a 39-year-old woman just a few weeks into her first pregnancy, wrote to tell me she had been put on the steroid dexamethasone to prevent a miscarriage--and to ask whether she. Dexamethasone is a corticosteroid used to treat a variety of medical conditions. The safety of using dexamethasone in pregnancy is unknown. In general, a woman should only take dexamethasone in pregnancy when she has a medical condition that clearly calls for use of the medication. In general is dexamethasone safe during pregnancy? Our betas are doubling nicely,but her FS gives it to people with high NK cells ,she has only slightly elevated I am sorry to bother you,but my wife has read something on internet about dexamethasone and is anxious since then. This drug readily crosses the placenta. Teratogenicity including increased incidence of cleft palate have occurred in animal studies, however, the relevance to human has been questioned.