If you take ibuprofen when drinking more than the recommended amount for women (about two to three drinks), you increase your risk of stomach irritation and bleeding. This is especially true for. If you take ibuprofen only on occasion, it may be safe for you to drink in moderation. Know that having even one drink while you’re taking ibuprofen may upset your stomach, though. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Bouvier on how long after drinking can you take ibuprofen: It's safe to take it immediately after or before. Ahh, the morning after -- leaving young people dizzy since 1962. When you drink, your liver and kidneys go into overdrive. They quickly try to get rid of all the alcohol they can as fast as they can. Ahh, the morning after -- leaving young people dizzy since 1962. When you drink, your liver and kidneys go into overdrive. They quickly try to get rid of all the alcohol they can as fast as they can. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Burns on is it ok to take ibuprofen after drinking: Even though most of the time it may be safe to take advil (ibuprofen) after drinking , but you have to be aware that alcohol can increase the risk of stomach bleeding caused by ibuprophen.So if you take it and start with black tarry stools or vomiting blood go to. I have had two, small, glasses of rose with dinner this evening, and I had a tiny bit of 'mickey finn' liqueur earlier (around 3pm). I am now experiencing excruciating pain and I desperately want some pain relief, but obviously I don't want to die. Advil (ibuprofen) doesn't take a toll on your liver like tylenol does. I've taken both while drinking and nothing has happened to me, but advil certainly is the much better option if you've been.