Xanax is usually out of the body within 2 days. If the person is aregular user of the drug it could take up to 7 days for the drug toleave the system. couple bars, put the powder in a shot glass, stir it up and take it down. he passed out within 10 minutes. i would say the best way to speed absorbtion/effects of xanax would be Re: how long does it take for xanax to work? Depends on 2 things how much was the dose (.25.5, 1mg, 2mg) and your tolerance and how much food you have in your stomach. If its a higher dose then you normally take I'd say 15-30 max and thats not on a full stomach I find that if I havent eaten recently the xanax hits me faster. Xanax is usually out of the body within 2 days. If the person is aregular user of the drug it could take up to 7 days for the drug toleave the system. How long does Xanax take to work? Alprazolam (Xanax) is a drug that relieves anxiety within about half an hour of oral intake. Most people who use Xanax say that a single dose kicks in 15- 30 minutes and its anti-anxiety effects last for a few hours. How to use Xanax. Read the Medication Guide provided by your pharmacist before you start taking alprazolam and each time you get a refill. If you have any questions, ask your doctor or pharmacist. How long does it take for Xanax to “kick in” or take effect? It varies among Xanax users. Due to interindividual differences, is understood that not all Xanax users will notice the medication “kicking in” (i.e. taking effect) at the same rate. i have recently been prescribed the 2mg extended release tablet (A 23 mylanta). 2 a day is my dosage. I'd like to know often ( in time form) how often it is released into my body compared to a 2mg instant release tablet. I take 1 mg twice a day so I think one of mine is like 4 of yours but I wouldn't suggest taking that many if your not used to it, as far as how long it takes it usually takes mine about 15 to 30 min.