Vicodin vs Lortab. Vicodin and Lortab are medicines that belong to a group of medicines known as narcotic pain relievers. Both of these drugs are mainly prescribed for giving relief to moderate to severe pain. Compare prices, print coupons and get savings tips for Lortab (Hydrocodone / Acetaminophen, Lorcet, and Zolvit) and other Pain drugs at CVS, Walgreens, and other pharmacies. Prices start at $27.02 Lortab (hydrocodone bitartrate and acetaminophen) is a combination pain reliever containing an opiate (narcotic) pain reliever, hydrocodone and the non-narcotic pain reliever acetaminophen, used to relieve moderate to severe pain. Norco, like all narcotics, may impair the mental and/or physical Lortab Description. Lortab is supplied in tablet form for oral administration. Hydrocodone bitartrate is an opioid analgesic and antitussive and occurs as fine, white crystals or as a crystalline powder. LORTAB® 10/500 (hydrocodone bitartrate and acetaminophen) Tablets, USP 10 mg/500 mg. DESCRIPTION. Hydrocodone bitartrate and acetaminophen is supplied in tablet form for oral administration. Lortab contains a combination of acetaminophen and hydrocodone. Hydrocodone is an opioid pain medication. An opioid is sometimes called a narcotic. When looking at Lortab vs. Norco, they are very similar. One of the primary differences you’ll see is the amount and ratio they have of hydrocodone to acetaminophen. How to use Lortab 10 Mg-325 Mg Tablet. See also Warning section. Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking. Learn About Lortab Abuse & Addiction. Lortab (also known as Lorcet, Norco or Vicodin) is a controlled-substance medication used for pain only available by prescription. Hydrocodone is used to relieve severe pain. Hydrocodone is only used to treat people who are expected to need medication to relieve severe pain around-the-clock for a long time and who cannot be treated with other medications or treatments.