You could try a drug that blocks LDL uptake in the intestines like Zetia, but it's not as effective as a statin. Many people will point out that your high HDL will offset the high LDL, but that is not always the case. Zetia received an overall rating of 5 out of 10 stars from 34 reviews. See what others have said about Zetia, including the effectiveness, ease of use and side effects. Zetia will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan. Zetia side effects Get emergency medical help if you have signs of an allergic reaction to Zetia: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Find user ratings and reviews for Zetia oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction Zetia is the brand name for ezetimibe, a drug that lowers LDL cholesterol levels by reducing cholesterol absorption in the small intestine. LDL ( bad ) cholesterol builds up in the walls of. Administration of Zetia with fenofibrate is effective in improving serum total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia as compared to either treatment alone. The effects of ezetimibe given either alone or in addition to a statin or fenofibrate on cardiovascular morbidity and mortality have not been established. 2018, Antioch University Seattle, Dennis's review: Zetia generic (Ezetimibe) 10 mg. Only $0,94 per pill. Effective Zetia online. Zetia (ezetimibe) is a drug used to help treat high cholesterol, and works in a different way than statins, which lower cholesterol by 35 to 60 percent in most patients and reduce the risk of heart attacks among them.