It’s weird how the Nexium did not help me yet caused flare-ups when discontinued. I am no doctor and can only speak from personal experience. I suggest you read the Fast Tract Digestion Heartburn book and follow the dietary guidelines. Nexium prescription assistance is sponsored by Astra Zeneca to help low-income and uninsured patients get expensive brand-name Nexium either for free or at a large discount. PS Card recommends RX Access for help in the Nexium PAP application process. How to Get Off Nexium. Nexium belongs to a class of drugs called proton pump inhibitors (PPI) that can help treat acid reflux, ulcers, H. Pylori, and other gastrointestinal disorders. Prolonged use of this powerful drug can also cause. Jeff, yes Nexium does help, that is what is so enticing about it. You can blithely go along eating and drinking everything you want and never really change the habits that contribute to the initial problem. So, yes you may need it to heal the attack that you had, but do think twice about staying on it. Nexium users may experience various side effects from the drug, and choose to stop taking it. These include abdominal pain, diarrhea and headache. There are alternative methods for controlling acid reflux that may help you quit Nexium, leaving you with fewer reflux complications afterwards. Nexium (esomeprazole magnesium) is a proton pump inhibitor that decreases the amount of acid produced in the stomach. Nexium is used to treat symptoms of gastroesophageal reflux disease and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. You could talk to the company, however, Nexium is part of a class of drugs called proton pump inhibitors (PPIs). Several types of proton pump inhibitors are available by prescription only. Hi Cougar- Wish you the best. I too am getting off Nexium. I was on 40mg for almost 6 years. My plan (hopefully it works) is to go to 20 mg per day for a week, then 10mg per day for a week, then every other day for a week at 10mg. I have recently stopped taking Nexium after @ 8 or 9 years.When I turned 40 my health went down the pooper and I've had numerous health issues making me re-evaluate what I'm putting into my body.So,long story short,with the help of my primary doc that I've seen for 20 years and my naturopathic doc,I've stopped taking the Nexium about 10 days. Stopping Nexium or Other PPIs: So how can people like you phase off drugs like Nexium without going through hell? First, never stop suddenly! Rebound hyperacidity can cause unbearable heartburn.